Wednesday, May 6, 2020

CCMB: Only centre pooling COVID-19 samples, To Culture virus in human lung cell


In India, the Centre for Cellular and Molecular Biology (CCMB), Hyderabad is the only centre to pool samples of COVID-19 in the country. The CCMB has now collaborated with Bengaluru based private company to take up a research activity.

Highlights

  • The collaboration is to grow COVID-19 virus in human cell lines. 
  • This will enable in-vitro tests of vaccines and potential drugs against the virus. 
  • In order to achieve this the collaboration is to use human lung epithelial cell culture system that was developed by the private company.
  • The entire research will help the scientists understand pathological and molecular characteristics of the virus.

About the research

  • The virus is to be cultured outside the host (human). 
  • During the culture, the collaboration will test for the efficacy of drugs and vaccines against the virus. 
  • So far, CCMB has been growing the virus on the cells that were collected from African Greek Monkey.
  • The collaboration will help to get a clearer picture about the virus.

Why in Human Lung Cell?

  • The Virus is said to affect the respiratory system of human body very badly. 
  • Hence, the lung cells of all the cells are easily attacked by the virus. 
  • Hence, lung cells have been chosen for the study.

Pooling

  • The CCMB is the only centre in India where the samples of COVID-19 are pooled. 
  • Pooling of samples is collecting the virus samples. 
  • So far 9 mutations of COVID-19 have been found. 
  • All such samples have been collected and stored at the centre.

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