Monday, May 4, 2020

USFDA approves emergency use of an investigational vaccine, Remdesivir


The United States Food and Drug Regulatory body recently allowed emergency use of anti-viral investigational vaccine Remdesivir to treat COVID-19 patients.

Highlights

  • The USFDA has approved the vaccine after an Indian-American physician, Aruna Subramaninan’s report on Remdesivir. 
  • According to the report, the vaccine shortened the recovery times of people that have fallen ill due to COVID-19 virus. 
  • The FDA has provided emergency use authorization of the drug.

Remdesivir

  • Remdesivir was developed to treat Ebola virus and Marburg virus. 
  • However, it was found to be ineffective in treating these diseases.
  • International Nonproprietary Name
  • Remdesivir is an International Nonproprietary Name (INN). 
  • The INN is provided to a pharmaceutical drug or active ingredient. 
  • The INN is issued in Latin, English, Russian, French, Spanish, Chinese and Arabic.

Emergency Use Authorization

  • The Emergency Use Authorization in the United States to approve drugs during emergency. 
  • Earlier, the US FDA had approved use of diagnostic and therapeutic tools to identify and respond 2009 swine flu outbreak.
  • In 2013, the FDA issued Emergency Authorization Use of CDC Human Influenza virus.

Remdesivir trial by WHO

  • WHO had launched 4 mega trials to treat COVID-19. 
  • It includes Remdesivir, HCQ (Hydroxychloroquine), combination of Lopinavir and Ritonavir and Interferon-beta along with the combination of Lopinavir and Ritonavir.

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